Antibiotics And The Antiviral Response

Antibiotics And The Antiviral Response


[music] Akiko Iwasaki: So my focus
is really trying to understand how viruses are detected
by the immune system and also how that information is utilized
by the immune system to mount a robust protective antiviral
immune response. What is new about this finding
is that we typically think of antibiotics as having
a specific effect on the bacteria. But what our
study shows is that it also has this unexpected
antiviral effect. She treated the mice first
with Neomycin and then when she infects the mice
with herpes simplex virus she saw resistance against
the virus and so Smita took this approach of treating germ
free mice which are mice that are, live without any
bacteria to see if the Neomycin still has an impact
on antiviral resistance. And she surely found that there
was resistance even in the absence of any bacteria.
We’re not promoting the use of antibiotics to treat
viral infections. However it is an important
finding because it shows that these typically
antibacterial compounds in fact have these antiviral roles
as well. [music]

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