Dr. Warren Rose, Fighting Antibiotic Resistance

Dr. Warren Rose, Fighting Antibiotic Resistance


[ Music ]>>Well, my research is in
an interesting area, I think, developing and infectious
disease. As you read more about
antibiotic resistance and problematic pathogens
worldwide, I think it’s an exciting time
to be in antibiotic development and antibiotic resistance. My research mostly focuses on
translating the patient setting or what we see in patients
back into the laboratory, trying to make solutions
for those patients and bring that back to patient care. One of the things I’m currently
working on is as we learn about antibiotics, you
have patients that respond to antibiotics and those that
don’t respond to antibiotics. And the organisms that we’re
treating seem to be sensitive so our question is why
do patients fail therapy? And so we’re trying to
get into the groundwork of understanding maybe some
immune responses in patients that can lead to antibiotic
failure and whether or not we need to use
antibiotics effectively in patients that have
underlying immune deficiencies that are not present
in their disease state. And so, kind of getting a basis of their immune responses
upfront and then merging our
antibiotic therapy into that response is an area
that we’re starting to develop and we’ve recently published
some papers in that area. And that kind of brings
it all together as far as using antibiotics
and managing patients in the teaching side, understanding why we
give certain antibiotics to certain patients. And then there’s a lot of
work that students can do on the investigator
perspective, too. It’s impressive to see the
interest of students that are in their first through
their fourth years as far as learning different research
techniques or understanding some of the clinical questions and research questions
that are out there. You can read in the textbook
how antibiotics are used but seeing them actively
used in complex situations where maybe a textbook setting
wouldn’t apply in every patient. And so understanding the
diversity of the patients to apply the antibiotics as far
as treatment and then taking that back into the
classroom and telling students that this is the ideal
way to treat patients but in the real world sometimes
ideal situations are not available and so you have to
be creative in how we use them. We have world renown
physicians that are practicing. We have a unique
patient population, such as transplant patients,
other immunosuppressed patients that present unique antibiotic
and treatment challenges. So that brings in kind of
an exciting area to practice and to do research in. And then the resources here,
I think, are second to none. So if we need anything on
campus, we want to collaborate with other investigators, it’s a
highly collaborative environment and the resources
that are able to do that are really outstanding. [ Music ]

Add a Comment

Your email address will not be published. Required fields are marked *