Is MDMA psychiatry’s antibiotic? | Ben Sessa | TEDxUniversityofBristol

Is MDMA psychiatry’s antibiotic? | Ben Sessa | TEDxUniversityofBristol


Translator: Neven Mazic
Reviewer: David DeRuwe 3,4-Methylenedioxymethamphetamine: MDMA. Now you’ve probably heard
of this compound in the context of the
recreational drug Ecstasy. But today I want to talk about MDMA,
not as a recreational drug, but as a potential
new treatment in medicine, and then a very important
treatment for psychiatry because MDMA could offer us,
in psychiatry, for the first time, the opportunity to tackle trauma. And psychological trauma, particularly that caused
by child abuse and maltreatment, is at the heart of all
or most psychiatric disorders due to anxiety and addictions. Psychiatry is in need
of this innovative approach because current treatments
are failing patients. Hi, my name’s Ben Sessa. I’m a child and adolescent psychiatrist. Now that means
I trained as a medical doctor, then specialized in mental health, and then specialized
in child and adolescent mental health. But for the last five years, I’ve been working with adults
with mental health disorders and addictions due to misuse of drugs. And that developmental
pathway of my own, from working with child abuse into adults
with mental disorders and addictions, has brought me to the door of MDMA. And I’m going to propose today that MDMA could be [as] important
for the future of psychiatry as the discovery of antibiotics was
for general medicine a hundred years ago. So when we think about child abuse, we think about physical abuse,
mental abuse, emotional abuse, sexual abuse, and neglect. And we think about noxious environments, we think about parents
with mental disorders, we think about parents
who are addicted to drugs, and social issues like poverty,
and poor housing, poor education. Now I’m going to illustrate
my talk today with a patient, and I’m going to call her Claire. Now, Claire was no single
particular patient of mine. Rather, she’s an amalgamation
of many different people I’ve met in the last 18 years working
as a medical doctor. She’s certainly not the worst. Now, what was Claire’s environment like
as she was growing up? Well, her mother was depressed. Unfortunately, the family doctor
didn’t have time to accurately diagnose
and treat depression. Rather, Claire’s mother was put
onto one antidepressant after another, never really got therapy. Claire’s mother also had a lot
of aches and pains, typical of what we call
psychosomatic symptoms in depression, and, as a result, the family doctor
put her onto opiate-based painkillers which she promptly became addicted to. Now, Claire’s father, he was alcoholic, and he was often not around,
in and out of prison, which is just as well because when he was there, he was physically abusive
to Claire and her mother. Okay, so what does this kind of chaotic,
frightening environment do to the developing child brain? I’m going to give you a brief
neurophysiology lesson, if I may. There’s a part of the brain
called the amygdala. Now, the amygdala is a very ancient part
of the mammalian brain, and many other animals,
other than humans, have an amygdala. The amygdala lights up when stimulated
by fear in the environment, by a frightening stimulus. It lights up and it says,
“Fight or flight, get out!” Now, there’s another part of the brain,
a much more sophisticated part, called the prefrontal cortex, and it’s right here,
at the front, above the eyes. Now, the prefrontal cortex,
only humans have, and it’s in the prefrontal cortex
where we use logic and reasoning to rationalize the situation, and we can use our prefrontal cortex to overcome that instinctive fear
response from the amygdala. Now, when Claire was growing up, she never knew,
from one moment to the next, whether the adult coming into the room
was going to give her a kiss, or a cuddle, or do a jigsaw with her, or were they going
to punch her, or kick her, or burn her with their cigarette. Or were they going to rape her. Because, throughout her childhood,
Claire was also subjected to sexual abuse. Now, there’s a group of disorders
called the anxiety disorders, and one of the most important is what
we call posttraumatic stress disorder, or PTSD. Now, PTSD, some of the core features: very low mood, anxiety,
high levels of anxiety, what we call hypervigilance – this edginess, this jumpiness. Exactly how Claire felt,
throughout her childhood and adolescence, never knowing whether the next assailant
or assaulter was around the corner. Another core feature of PTSD,
what we call re-experiencing phenomena, flashbacks, in which the patient
has sudden remembrances of these painful traumatic memories. They can just pop
into the head at any time, triggered by some cue in the environment. And when they have those experiences,
those daytime flashbacks, they relive the trauma
in all the sensory modalities, and this results in them
freezing or dissociating to try and block out the pain. Now, Claire experienced all of this
as she was growing up. High levels of self-harm and suicide
are associated with PTSD. Claire would cut her thighs
and her breasts, pretty common form of cutting
in children who’ve been sexually abused. She was being sexually abused
by clients of her mother because her mother had moved on
from the addiction to painkillers and was using street heroin
when Claire was a teenager. And because of the way
the war on drugs has set up, that reduces access to treatment
for people with opiate dependence, she had to pay for her heroin
use in sex work, and the clients
would sexually abuse Claire. Now, it’s very hard to treat PTSD
and it has a high treatment resistance – 50% of people do not respond
to the traditional treatments. How do we treat it? Well, we can treat it with medications.
We can treat it with psychotherapies. And the medications we use,
there’s a broad range of drugs. No single drug,
and this is very important, no single drug cures PTSD. Rather, we treat
the disorder symptomatically. If the patient’s depressed,
give them an antidepressant. If their mood fluctuates,
give them a mood stabilizer. If they can’t sleep, give them a hypnotic. And if that edginess and that fear
spills over into paranoia and psychosis, give the patient an anti-psychotic drug. And they have to take
these drugs day in, day out, for weeks, months, decades. They have to keep taking them
because the drugs we use to treat trauma, when it’s due to this level of severity, do not attack the root cause of trauma. They paper over the cracks. A good analogy would be taking aspirin
or ibuprofen when you have a fever. Now, fever is caused by an infection,
by a microorganism. Sure, you can take
paracetamol or ibuprofen, and this will lower the temperature,
make you feel a bit better, but it doesn’t attack the root cause. And that’s what we do when we give
these patients these daily SSRI drugs. We paper over the cracks, we maintain the symptoms
at a manageable level. We also use psychotherapies to treat PTSD,
and there’s again a broad range of these: DBT, CBT, EMDR, trauma-focused
psychotherapy, CAT, APT … Now, all of them have
a pretty similar approach which actually is an old wives’ tale which is: a problem shared
is a problem halved. “Let’s talk about your trauma. Claire, tell me about your rape.” Now that’s fine for 50% of patients, but for a significant half,
they just cannot do that. As soon as Claire is asked to talk
about her rape, she freezes, she flees, she drops out of treatment. Now, by the time she was 15, Claire had been removed
from the family home, and she was brought up
in a succession of foster placements, and children’s houses,
and hostels where the abuse continued. She would self-harm cutting,
and she started drinking, and, by the time she was 18,
she was using heroin as well. Sometimes working in psychiatry
can feel pretty desperate, can feel pretty hopeless. Sometimes it feels as if psychiatry
is a palliative care profession. And this is the truth
because the treatments we use do not get to the root cause
of the problem, the trauma; they paper over the cracks. And I think the pharma industry
knows this, and they queue up, and they provide us
with product after product to give to our patients
that doesn’t quite cure them, but it gets them
slightly better to function. And they have to keep taking them. I would say that we’re
in psychiatry, today, where we were in general
medicine 100 years ago. Now, 100 years ago, in general medicine, humanity was losing the battle
to the infectious diseases. Oh, we were very good
at classifying and diagnosing them. We knew who got smallpox. We knew people died
of post-operative surgery. We knew there were microorganisms,
but we didn’t have a treatment. And then, at the beginning
of the 20th century, we discovered the antibiotics. Not symptomatic treatment, but treatment that goes
to the core of the cause, and we started getting
on top of infectious disease. Now, psychiatry, today,
is in a similar place. We’re very good
at classifying and diagnosing. Our epidemiology is superb. We write these thick diagnostic manuals. We know who gets depression. We know who gets anxiety. We even know the cause: trauma, child abuse, maltreatment, poor social conditions. But our treatments are lousy. And I’m quite shocked
the way the empathy switch and our understanding of these patients
seems to be switched off. We have lots of gushing sentimentality for the little five and six-year-old
who’s being abused, and we throw money at our television sets on these campaigns to improve the lives
of these poor little innocent victims. But let me tell you what happens
to that little five- or six-year-old when they’re 11 or 12. On goes the hood, start smoking weed. When they’re 16, they’re
buying and selling amphetamine, by the time they’re Claire’s age,
in their mid-20s, they’re addicted to heroin and alcohol. And, suddenly, we have lost our empathy. These people are public enemy number one. “It’s your fault, Claire. You brought this upon yourself. It’s your lifestyle choice.” And I’m quite shocked,
and having worked in pediatrics and seeing the developmental trajectory
that is so inevitable, from early trauma into adolescent, and then adult
mental health and addictions, we have to hold on
to that sense of compassion and evidence-based understanding
about the developmental trajectory there. So it does sound desperate,
but all is not lost. MDMA. MDMA has some fascinating qualities. Indeed, I would suggest
that if you were to invent a hypothetical drug to treat trauma, it would be MDMA. The way it works, in terms of receptors
and subjective psychological effects, ticks all the right boxes. At one level of receptors,
it causes an increased positive mood, lowering of depression,
lowering of anxiety. At another group of receptors,
it speeds the patient up, mild stimulation which motivates
them to engage in therapy. At another level, it relaxes
the patient, paradoxically, at the same time as the stimulation, and this puts the patient
into the optimal arousal zone where they can engage in psychotherapy. But perhaps the most
important thing about MDMA, and the most important clinical tool, is its ability to provide a sense of empathy, and understanding,
and emotional security. It can hold the patient in a place where they can think about
and access their trauma like they’ve never been able to do before. One of the ways in which MDMA works is it increases the release
of a hormone called oxytocin. Now, oxytocin is released from the brains
of breastfeeding mothers. It’s a hormone that engenders
a sense of attachment and bonding, and that’s what’s happening
in the patient who takes MDMA. And, also, it acts
directly on the amygdala to reduce that fear response, while, at the same time,
boosting the prefrontal response, allowing the patient
to see things in a new light, a positive light. So let’s go back to Claire. She’s 40 now. She’s been in and out
of psychiatric hospitals, having tried to take
her own life in the inception. She’s been on all the antipsychotic,
antidepressant, mood-stabilizing drugs. She’s tried all the psychotherapies,
but she cannot engage because she will not talk
about her feelings. So she comes into a course
of MDMA-assisted psychotherapy. What does it look like? Well, it’s weekly sessions,
maybe eight, ten, twelve weeks long, with two therapists, male-female pair. You do not take MDMA every day,
you do not take it every week. Over that course of 12 sessions,
you’ll take the MDMA three times, and the other sessions, you talk about the material
that’s released on the MDMA session. So what does Claire actually feel
when she takes this MDMA? What she feels is a sense
of warmth and understanding, and a sense of containment within that relationship
she’s having with the therapists. MDMA is like a life jacket,
like a bulletproof vest, to wear to go into battle
with your trauma. This is not ecstasy! She’s not enjoying some
raver’s euphoric ecstasy delight. This is still trauma-focused
psychotherapy, and it’s still hard
and distressing for her, but she can just about do it
with MDMA on board. So when the therapist says,
“Claire, tell me about your rape” – In the past, just the word rape,
and she’d be out the door, but on MDMA she says,
“Yeah, I can talk about that! I can see him now coming into the room, I can smell the whiskey on his breath, and I can feel the stubble on his face
as he’s raping me.” And she talks about it,
and she explores it, and she reflects upon it, and she can begin the process of healing. And from here, she can start her journey. She can attack the root cause
of her problems, not just maintain the symptoms at a level. So, does it work? Well, we’ve known about MDMA
for a very long time, and, indeed, we’ve used MDMA
in underground therapy for 30 or 40 years, and there are thousands
of positive anecdotal cases. I get five emails a week
from all over the world, “Dr. Sessa, I’ve had PTSD for years. I’ve tried everything,
and now I tried MDMA, and I’m starting to make a breakthrough!” Now, anecdotal reports
like that are interesting, but they’re not science, so we’ve done the science and some important studies
in recent years. Big study in the States showed
that a single course of MDMA therapy, 16-week course, patient takes MDMA
three times, tested against the placebo – At the end of that course, 85% of the people no longer met
the diagnostic criteria for PTSD. Not just a relief of symptoms,
they didn’t have PTSD! Now that cohort were then followed up
three years later, the same – no PTSD. Many of those people had come
off their daily medications. They were cured! We don’t use the “cure”
word in psychiatry. We’ve become learned helpless
in this position of … This is the truth! If you’re diagnosed
with a severe mental disorder, like anxiety or depression, in your 20s, and the developmental route
of that disorder is severe child abuse, there’s a pretty good chance,
and I’m sorry to say this, there’s a pretty good chance you will still be going to psychiatric
clinics in your 60s and 70s. Now that is not good enough, and we’re in this position
because we’re not tackling trauma. So, it works, but is it safe? Well, when we think about
safety of clinical MDMA, what we must not do is look at the risks
of recreational ecstasy. I don’t even know what ecstasy is anymore! Ecstasy is over here; what is ecstasy? Some dodgy pill, bought in some
dodgy club, off some dodgy geezer, that may or may not contain MDMA, plus or minus whatever
far more toxic substance. And indeed, when you hear
about the very high-profile deaths of people who take ecstasy, it invariably is not MDMA. So, let’s not look at ecstasy
as a measure of MDMA. Let’s look at clinical MDMA. Now, when you use clinical MDMA,
you take it under medical supervision, it is pure. The MDMA that I’m using
in my studies is 99.98% pure! Very expensive! (Laughter) We do it under medical supervision with a doctor, and a nurse,
and a psychologist. And under those conditions, the risks
are reduced to an absolute minimum. Indeed, after 40 years of MDMA research, there has not been a single serious
adverse drug reaction, not one! And certainly no deaths. So, we need to do this research, and we need to do this research
in an evidence-based, compassionate way, looking at the data. We need to ignore
the sociopolitical agenda that says any drug
that’s being used recreationally must also be very bad and dangerous. That sort of attitude hampers research. And we need scientists to drive this. It works, it’s safe, and it offers patients like Claire,
for the first time in their life, an opportunity to break through
from that trauma and not become a lifelong
chronic PTSD sufferer. So, where are we going with MDMA research? Well, we’ve had some studies,
we’ve got more coming here. I’m doing a study
in Cardiff with neuroimaging in which we’re going to give patients
with PTSD MDMA and placebo, and we’re going
to look at that relationship between the amygdala
and the prefrontal cortex. We’re also doing a study here in Bristol, giving patients with alcohol
use disorder MDMA, because underlying the root
of this addiction is trauma. So, this is an exciting time. Now people say, “This is controversial!” And indeed, I was introduced
as a controversial speaker. I’m not controversial. I’m a very boring conservative doctor. I like data. I like evidence-based data
that helps my patients. I’ll tell you what’s controversial. What’s controversial
is that more people have died returning from Afghanistan and Iraq because they’ve committed suicide
because of their untreated PTSD than ever died in the conflict out there! That is controversial,
and that is unethical! So, this is an important time for science. MDMA could be the antibiotic
that psychiatry has been waiting for. We owe that population
of patients who are being failed, we owe them this research! We owe this to Claire! Thank you. (Applause)

100 Replies to “Is MDMA psychiatry’s antibiotic? | Ben Sessa | TEDxUniversityofBristol”

  1. Hi Ben,
    This talk of yours brought tears to my eyes. Thank you so so much for your work in this area and for helping people like myself (and others who are much worse off). Your understanding of human nature and practical use of empathy is what the world of mental health needs right now. Long story short: I grew up with multiple family members having mental illnesses in an environment similar to what you described in this video with "Claire". In a loooooong roundabout way this led me to rehabilitating traumatised dogs from shelters, which is what I now do! I have been diagnosed with PTSD & BPD and all that comes along with those disorders. I've been lucky enough to have experienced the use of MDMA and for the first time in my life I felt "bonding" with another person. I finally knew I'm not alone. It's all I'd ever wanted. Even now I can still replicate that feeling naturally – years after the MDMA wore off. Ending the stigma around these drugs will enable SO many mentally crippled people to stop suffering and become happy, productive members of our society. I'd be more than happy to volunteer any information you want for your research, for what it's worth. Thank you again and all the best from Malta <3

  2. I wish they had this study in NZ, I'm on the brink of suicide after suffereing from c-ptsd for over 30 years! I've trued so many thrrapies including emdr, meditation, energy healing but haven't heald and in fact have got worse!

  3. Listen…I'm an ex practicing RN….who grew up with major depression….but had good parents and love in my life…which created Hope, love and allowed me to get edu-ma-cated as far as society is concerned…got my simple RN degree…and failed miserably at holding various jobs d/t anxiety and depression all the while.

    Recently…after trying food therapies (if you will), to past experiences with AMA's / Prescriptions for toxic antidepressants….I kept failing.

    Now…I take one good "inhalation of THC/CBD" as a function of smoking which causes the methylation of chemicals in the marijuana plant to help me.

    Forget the chemistry (which is simple chemistry)…I'm helped to: sleep, be motivated, energized by actually sleeping at night now….can keep a job….and am a "high" tax payer now that I can work again successfully.

    Still,….I could go to jail????for smoking something that MY GOD made for me…unrealized for over 50 years….absurd.

  4. You know the weird thing about this talk is how hard it is to find in any search results. On yahoo or TEDx. Seems like it's being censored.

  5. confused about your made up 'Clair' story……heroin takers have no sexual desires whatsoever, so why where they all jumping into bed to sexually abuse 'Clair' ???? -pray tell……..oh, your after more funding….ok, right, got it.

  6. I have c-ptsd and I've tried pretty much every treatment EMDR, hypnosis, energy healing (many different types) all.sorts of meditation, psh, rewind, talk therapy, medication and nothing works. Feel suicidal.every day! Feel unloveable feel useless never been able to achieve anything never been loved

  7. I used ecstasy and later was told that something was wrong. It's one of those things that seems to affect everyone in a big way. Plus you can't turn back the clock..

  8. Currently undergoing DBT for PTSD and also very passionate about pursuing a career in mental health. Of particular interest is the bulk of your talk, and alternative treatments to such root causes of trauma.

    I plan to self educate before school and was wondering what public resources you could recommend? Both Psychology and Psychiatry are in my sights and the research is exciting!

    Thank you Ben for your passion and compassion. Well done 🙂

  9. some people here feel justified to smoke weed and they are hipocrites ..any mood altering substance is considered drug abuse so to get high and feel better…all problems start from family everything bad is inherited to our beeing,people(parents) dictating to others what is good and what is bad without proof or criteria or examples are considered dangerous and hipocrites,thats why in ancient times a teacher was considered the same value as a parent..if our families fail miserable we could at least have a teacher(scienticst pedophyciatrist) to our schools that would show as values and examples..So now you can see my point goverment – education/science-family is how the river flows and in my personal opinion no1 is going to allow or justify this project and research they will keep minds like the speakers to be underground and not mainstream they know how to play the game they allow small explosions so the pressure wont explode at once and ruin their empire (drug companies farm companies weapon companies pleasure companies and so on)

  10. Many thanks, very interesting. I hope it will be recognized as an evidence based drug soon. What do u think about other drugs such as Ketamine in this context (i.e. a new antibiotic in psychiatry) ?

  11. Miley Cyrus shaking her ass: Millions of views
    This: 50k views.

    I really feel sorry for the human race.

  12. Writing my Masters Thesis on this and kept coming across "Sessa." Glad to find his Ted talk on such a wonderful and fascinating subject.

  13. For legalizing MDMA in the US and Canada: https://fundrazr.com/campaigns/LegalizingPsychedelicMedicine/pay

  14. how dare you associate marijuana with mental instability and harder drugs later in life. that is an outdated, and debunked view on cannabis. get your shit together.

  15. Thank you so very much, Dr Sessa, you have a truly outstanding and far healthier approach to the absolute curse of PTSD. I wish you the very best in all your future endeavours – and I will be watching any future broadcasts with great interest!! Please keep up your vitally important and GREAT work!! Dennis

  16. Dr Sessa you did not sound like i thought you would from reading your books ! I am a mental health nurse student and i have been interested in this field for a few years now. fantastic talk. I have met consultant psychiatrists in this country who agree with you but it is a political minefield i have been told. I support this and will continue to. People will happily have there heart shocked during a heart attack but ECT is looked down upon for severe depression… why ? Mental health deserves its penicillin as you gracefully put it. 100% agree with you

  17. ketamine, mdma, dmt and psilocybin are amazing drugs, i cant say ssris benzos and other pharmaceutical drugs arent though, personally they have helped me so much

  18. I find what is worse that people that also that have been traumatised and I don't mean those that have little symptoms or no symptoms of ptsd but those that have had some or different symptons of ptsd they don't have much compassion towards others!

  19. There is no “Cure” for the disease of Addiction. The use of Alcohol, drugs, pharmaceuticals and now legal marijuana are triggers for anger, fear, paranoia and rage. It is the reason why our society is like it is today…When you stop using drugs or drinking alcohol you cannot start again. If you do it will be like you never stopped and it will get worst. The fatal progression of the addiction disease never stops. It is the only disease that tells you don't have a disease. Total abstinence for the rest of your life is the only way to survive.

  20. I truly need this. Not just MDMA because I can find it on the street with the right amount of money, but MDMA therapy. My PTSD has basically crippled my entire life, and I have in fact dropped out of more than one therapy group already because I was getting NOTHING out of it. I'm 27 as of TODAY, and when one of my doctors said they want me to speak to my father about his medical history, I kept trying to say no but ended up having a panic attack before the doctor would stop…

  21. Low dose MDMA is effective in depression but….not really a long term cure. It does provide safe symptom relief and help adjusting to society, it's far superior to typical SSRI and SNRI drugs. I think Psilocybin has more long term benefits but MDMA is approved over ANY SSRI I've come across.

  22. problem is, as soon as an effective drug or treatment is discovered to be effective, Big Pharma via their cohort organization the FDA makes it illegal. why? because they will lose enormous profits from curing people. they NEED to have people sick, the more the merrier for them. welcome to fascism.

  23. Watching this video has literally made me start crying. I have been clinically depressed and anxious through my whole life due to child abuse and molestation. Growing up I was suicidal and felt I couldn't connect with anyone. By the time i was 16 I had already been in and out of 2 rehab facilities. After being on multiple different cocktails of prescriptions I started using various drugs, including things like, lsd, mushrooms, cocaine, and various pills, which led me to rehab again. I started transitioning from as a transgender person which alleviated a good many of my problems and helped me become gradually sober, but did little to cure my anxiety and childhood problems. After getting raped I realized I needed to start talking to a therapist again, this time i was finally open to start talking about my issues as opposed to sitting there for hours getting no where can I was so scared. We discovered i had PTSD, but even with all her tricks we couldn't get me to say a lot of things I needed to in order to work through my ptsd.

    Leading to this last week, I had heard about MDMA being able to help with PTSD and managed to find some that I know was at least mostly pure. Upon taking it I had a huge panic attack, ones that usually would make me disassociate for hours and stare in trauma, and started to think about all the things that had happened in my life. After 10 minutes the MDMA had brought me back to earth and was almost telling me things were okay. I began to reflect and question why how I felt about everything and was finally able to attack my thoughts head on and was able to, in a sense, start a dialog with myself and finally allowed myself to talk about it, to feel it, and to accept it as it with honestly. I also was about to see how I though about it and could allow myself to realize it's not my fault.

    Since then I have been able to keep the dialog with myself and remain honest and positive about myself and it has truly changed my life in a way I never thought it could have. I never thought I would be able to talk myself out of a anxiety driven ptsd disassociate episode and process them in order to pull myself out of it and ultimately grow and love myself.

    This ted talk has changed my life and makes me cry because I'm so happy I can finally move on with my life after 21 years.

  24. I don't smoke weed, but what's wrong with people smoking weed. Now, if someone's doing it constantly, that is a problem.

  25. No, it is not okay to still be going to psychotherapy in your 60's when you began in your 20's. I have to believe I will not be experiencing flashbacks and such that much longer -_-

  26. I wonder what the difference is between taking MDMA and magic mushrooms. I mean you hear similar things about magic mushrooms and psilocybin.

  27. MDMA changed my social life. It also absolutely changed my friend's life. He used to be uncomfortable with himself and really not socially skilled. He is now so much more extroverted and happy with himself.

  28. Congratulations Ben for challenging and exposing the controlling institutions, big pharma's and others in the health professions that make billions of dollars out of the misfortune of others. Your research evidence is outstanding and your presentation excellent. Let's hope there is progress from your experience, knowledge and wisdom. We do owe this to the people who suffer mental illness.

  29. 99.98% pure? Either mis-informed or lying because MDMA can only be 84% purity. The other 16% is a HCL salt. Besides that booboo, love the talk!

  30. If you come up with a way to fix me without the use of prescribed daily Xanax, please contact me. I would willingly volunteer. But I think my genetic predisposition and my life experiences up to age 35 years old would prove impossible to succeed. I have a great life now with two highly achieving children and a supportive husband. I don’t work but I obtained a college degree. I shouldn’t complain, I’d say that’s a success many don’t get to experience.

  31. This video was uploaded in during the very time frame that I was using MDMA to cure my c-PTSD. Three self sessions over 8 weeks. In those sessions, I was able to see the source of what I'd been holding for so long, reframe the memories, and also find & correct the source of my emotional instability. I'm highly intuitive/introspective, and have a knack for using these particular tools on my own to solve my problems. In general, however, I'd highly recommend this be done in a therapeutic setting.

    I will never go back to that despair-filled anxious mess that I was just 3 years ago.

  32. One day i took some with my daily dose of anxiety.. what i get was some weird paintings and a mouth chewed off.. I think everything can help what get you out of normal running but psychologists cure the things not the drugs.

  33. yeah sure, but what he said about mdma applies to medicines too. they work similarly helping in progress in therapy.

  34. I think XTC saved my life. I was thinking about suicide, tired of my life completely, then my friend bring some pills and we take. The effect was so strong and I dance all night and hug and speak with my friend. I was so happy. After that, I decided, that I need to change many things in my life. I took these pills like 6-7 times and everytime it gave me something important, that helped me to understand the world and don't compare and judge other people. After two months of using it I left Russia and went to travel south east Asia for one year. Without money, only hitchhike, sometimes sleeping on the benches on the street, but usually I met very good people, who was kind and help me on my travel. I think it helped me to get rid of negative feelings in my mind. It's almost impossible to find mdma in my hometown, and in XTC they add amphetamine, so it's has downsides, but still it helped me. Maybe someday I will be able to try pure mdma with great people, who will help me to overcome the pain that still remains somewhere very deep in my heart. I think the system of this world sets mdma as illegal drug, cause this drug make people happy, but system don't need happy slaves, it needs sick, depressed and controllable slaves, that's why in Russia alcohol and tobacco everywhere and very cheap. I saw how alcohol destroyed my uncle and many friends. Wish everyone to be happy!:) From Russia with love)

  35. Unless you've been bombarded with antidepressants over the years (that you stopped taking finally) and even a small amount later sends you into worse depression that takes weeks to recover from. Never will I try this again. Not for everyone. My experience is that trauma work – serious, mindful clear-headed work over the long run is what helps.

  36. If only we could get law makers out the past. And allow scientist to study and work with these things.

    Instead of criminalizing them and letting the drug war continue to destroy the world

  37. It is not methamphetamine it is methylamphetamine…. Every source on here has it wrong. The process is spot on. But at least please let's get the name correct in the name of Sasha

  38. As someone who has used mdma many times it has helped me reduce a lot of my anxiety. I would say that for people with severe anxiety it is an extremely helpful compound but it should definitely be taken with care. I would advise against mixing it with alcohol and other drugs as it could be potentially dangerous and it may dampen down its effects.

  39. Years ago I had a girlfriend whose mother died of alcoholism like 10 years before we were together,, during the time when we were together we were eating ecstasy on the weekends doin the rave thing rite, this girl had mentioned at one point as I was getting to know her that she could not picture her mother's face unless she looked at her picture ,,, one night after partying having had several pills a piece throughout the night we get back to my house and she had this experience where she felt like her mother was present with us in the room and of course at the time the thing was dancing right so she decided that she wanted to dance with her mom in my living room and she invited me to do so with her so I obliged,, a few days later we talked about that experience and she said she had peace concerning her mom and from then on she could picture her mom's face with out looking at a picture.. I don't condone drugs anymore but I have to admit, what I witnessed taking place in that girl was pretty amazing…

  40. I took my first this December( 70mg, then 50mg two hours later. My body weight is 55kg). I plan to leave at least 4 months between an use and the next. My reason for doing MDMA is more therapeutical than recreational(although I do both in one session, they are not mutually exclusive uses). During these months before next use, I will try to apply the epiphanies I got from my first session to grow and internalize the lessons, that way I can get new and better lessons next time.

  41. I cried when i watch it. everybody should watch this video, it must be mandatory. i wish there were some subtitles for those who do not speak english well

  42. Fantastic Brilliant Fabulous.
    Exceptionally well spoken!
    Once in awhile we get a little glimpse at the true intelligence in which this world could have already been held up by many years ago. If it weren't for the ever turning wheels that are relentlessly driven by the dominating greed and Vail of the sad but essentiall stupidity that fuels this heartless destructive machine that is our current global political world.

  43. 0:50 and 9:46 the fact he is suggesting that all psychiatric disorders are caused by trauma is simply not true and I think it is unfair to put MDMA as a cure all drug for many disorders when really it is only effective (very effective in fact) for PTSD.

  44. What a great talk! It was thorough and relevant. Not a single dull moment. I love how Dr Sesar talked about Claire, it made it so much more relatable. He said she is not just a single patient but an amalgamation of all his patients. It helped me understand and be more emphatic towards those who suffer from it. I do hope MDMA is the antibiotic psychiatry has been waiting for. Thanks for this talk.

  45. Antibiotics were a mistake they are feverishly trying to compensate for. Omniresistent bacteria and viri will prove this, in the future.

  46. Why don't they decriminalize MDMA or legalize it altogether? I'd rather be around someone turning to MDMA instead hitting vodka or whiskey

  47. I really liked the way you highlighted the need to be compassionate towards people. You don't know how they got to be that way. Are you looking for any volunteers for your trials?

  48. I am the guy who has been in therapy since age 21 and at age 63 I still am in therapy and On a ridiculous amount of medication
    Is there any way for me to get treatment in the states? Even in a study

  49. Son zamanlarda bir çok psikoaktif maddelerin yarattığı etkenlerle verimli sonuçların alınması oldukça ilginç

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