‘Shock and Kill’: A Hope for Curing HIV

‘Shock and Kill’: A Hope for Curing HIV


Today, patients with HIV are treated with
drugs that stop the virus from multiplying. But these treatments are not complete cures. When HIV is active, drugs can find and kill
it. But even when it’s not multiplying, HIV can linger for years in the DNA of immune
cells called memory T-cells. These infected cells can go into hiding – exactly
where and how they hibernate is still a mystery. One way to cure HIV – not just treat it
– is to destroy these viral reservoirs, in an approach called “shock and kill.” We can shock a latent T-cell with chemicals
that force it to wake up and make RNA. Once the cell is awake, it starts churning
out copies of HIV again. Now, drugs can home in on these HIV factories
to kill the virus and the infected cell. The key to making this work is to find out
where latent cells hide – and how to kill them efficiently. Once we figure this out, we can test “shock
and kill” as a way to cure HIV.

10 Replies to “‘Shock and Kill’: A Hope for Curing HIV”

  1. This is a great explanation! Hope this approach will end the need for lifelong drug treatment.

  2. Accurate and simple explanation. It's important to point out that, while scientists do know how to cure HIV, they don't know yet how to make it work; with the ever-advancing progress in medicine, I think we can hope for a cure to be created in the coming years.

  3. Its easy if I had a lab, doctor participation,,, simple I can cure AIDS HIV CANCER ANY BACTERIAL INFECTION EBOLA,, BUT NOBODY WILL LISTEN TO ME OR HELP ME…

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