The Ebola Virus Explained — How Your Body Fights For Survival

The Ebola Virus Explained — How Your Body Fights For Survival

What makes Ebola so dangerous? How can a virus overwhelm the very complex defense system of the body so quickly and so effectively? Let’s take a look at what Ebola does. (Theme music) Ebola is a virus. A virus is a very small thing. A bit of RNA or DNA and a few proteins and a hull. It has no ability to do anything by itself whatsoever, and can only survive and proliferate by infecting cells. To avoid this we have the immune system. The immune system is super complex so we develop a visual system that makes it easy to understand. So it looks like this: Let’s concentrate on the part that is critical to understanding Ebola and ignore the rest. So usually dendritic cells will activate the army of anti-virus cells, support cells and anti-body factories that work together with the guard cells wipe out the infection in a matter of days. But when Ebola strikes, it directly attacks the immune system. Some of the first cells it takes over are the dendritic cells, the brains of the immune system. The Ebola virus enters a dendritic cell by binding into receptors for cell transport. Once it is inside, it dissolves its outer hull and releases its genetic material, nucleoproteins and enzymes. In a nutshell it takes over the cell, disables the cells protective mechanisms and reprograms it. The cell now becomes a virus production machine and uses its resources to build Ebola viruses. Once the cell is saturated, it dissolves the cell membrane and millions of viruses are released into the tissue. The virus not only prevents the dendritic cells from activating the specialized and anti-virus forces, it manipulates them into sending signal proteins that tricks specialized cells into ending their own life’s prematurely. So the immune system is seriously disrupted and unable to react. When the virus rapidly multiplies, we’re talking billions, there are cells that should deal with infected cells, the natural killer cells, but they also get infected and just die before they can prevent the disease from spreading. At the same time Ebola infects the guard cells of the body macrophages and monocytes, not only managing to circumvent their defenses, it also manipulates some to signal to the cells make up the blood vessels telling into release fluid into the body Usually this makes sense, but in this case it just causes mayhem. All of the body’s neutrophils are activated awaken by the virus and the macrophages signals then are not very effective against viruses and should not be involve in this fight and begin to do lots of stuffs they shouldn’t do. The neutrophils signals to the blood vessels to release more fluid causing internal bleeding. Another area of the body Ebola attacks is the liver. The virus finds it very easy to enter the liver and it quickly starts killing loads of liver cells and causing organ failure and more internal bleeding. And all those things are going on at the same time. As the virus spreads, it’s like nukes exploding every where. One incident of this in one region will be problem enough But now is starting to happen everywhere at once. All the mechanisms of the immune system have evolve to handle infections work against you. And the virus continues to spread and spread. And finally begins to infect more and more body cells while the body desperately struggles to stay alive. In a desperate last effort to turn the tide the immune system launches a cytokine storm. A cytokine storm is an S.O.S signal that causes the immune system to launch all of its weapons, all at once in a desperate kamikaze attack. This hurts the virus but leaves behind tons of collateral damage, Especially in the blood vessels. Paradoxically the healthier the immune system, the more damage it can do to itself More and more fluid leaves the blood stream. Blood pours after every opening of the body. You become seriously dehydrated that just not now blood left to supply the organs with oxygen and cells begin to die. If you reach this point the chance of you dying is very high. Currently six out of ten infected die from Ebola. Wow! Ok. Ebola is nasty. So it’s time to panic, right? No, not even close. The severity of Ebola gets paper sold and YouTube videos shared so everybody is talking about Ebola. But currently the only way to get infected by Ebola is to come into contact with the body fluids of a person who shows symptoms Or from infected bat. So just don’t do that. Ebola has killed 5,000 people since June 2014. The common flu kills up to 500,000 people each year. Malaria causes up to one million each year. 3,000 people every single day. Ten children since this video started. So even if Ebola is terrible and scary, don’t let yourself be scared. The most infectious thing about Ebola is the media hype around it. You could learn a bit more about the immune system though Transcription made by Miriam Delgado Subtitles by the Amara .org community Revised by: Ace Ervite

100 Replies to “The Ebola Virus Explained — How Your Body Fights For Survival”

  1. 3:34 SARS and bird flu can also trigger that last-ditch kamikaze strike. The result's the same: The invader is beaten back, but it's a Pyrrhic victory for the immune system because of all the heavy collateral damage it leaves behind.

  2. We should make an vaccine against it and via the Crispr method we can separate the ebola gene code from our natural cells' genetic code, so by this . Those stupid ebola will die and we will be saved from its wrath…

  3. Remember when we started bringing infected mother fuckers over to the states? Because, yeah, let's take that risk so we all can die horribly.

  4. Kurzgesagt: Ebola is killing 6 out of 10 people infected. Should we panic? No! The whole universe will die one day so, chill out!

  5. Plague: immune suppression mutated
    Plague: Internal hemorrhage mutated
    Plague: Total organ failure mutated
    Plague: Cure completed 95%
    Plague: Your disease is killing too fast

  6. Boom bang boom boom boom boom boom boom boom boom boom boom boom boom boom let’s go get the super weapon boom boom boom boom annihilate annihilate annihilate annihilate annihilate boom boom boom boom boom boom explosion explosion explosion explosion boom boom done

  7. All these specific attack strategy and such accelerated spread rate within the body clearly shows its genetic engineered nature and the twisted mind of whoever the fuck made it.Definately a white twisted mind.

  8. It's so dangerous and scary because it's highly contagious and 9 out of 10 chances are it'll kill you in a horrifically awful way once you catch it, not 6 out of 10. You can catch it from sweat. Aids has never been on that level of scary.

  9. I've got a cure, we make a new type of cell
    its a cell that's only purpose is to destroy virus' and never stays around in the body for long periods of time
    so there would be no reason to bring in supplies into the cell, so there's no way the genetic makeup of ebola can get into it
    it would kill the bad cells, and replace them, it would have to be a weekly vaccine, but after a while, the ebola in your system would die out
    and by replacing the old cells, it would trick the body into not making new ones cause the ones that are active are still alive, effectively, killing the ebola virus for good
    the new ones would die out over time, and the body would start making new cells
    it may also take a quarantine of the body to make sure nothing else gets into your body, or if ebola re-enters the body, or stays dormant
    it would allow scientists to keep an eye on the patient
    the process would only take 1-3 months, and all we have to do is discover more about editing genetic makeups
    this cure could be done with any cell, even a strain of ebola, actually, remaking a strain of ebola to cure ebola is like making a spy
    if a regular cell entered, the ebola would go full force on it, and overpower it
    however, if done to strains of ebola, it could sneak on by without getting noticed, and maybe… even turn back infected cells, or make them immune
    the only catch with it is that we need more intelligence on editing DNA and RNA

  10. It's kind of scary to have had to get so close to ebola to do the research and data collection to figure out where it comes from, what its symptoms are, and why people were mysteriously dying.

  11. Why the heck have people thumbs downed this video? It’s an educational video not a vote if you like Ebola or not. Wth?!


  13. Kurzgesagt the death statistics aren't apple to apple comparisons. You should have published estimated influenza and malaria deaths for the same time period as used to measure the Ebola deaths

  14. producers: so we have the perfect idea for the season finale of Cells at Work! It promises to have lots of action scenes and dramatic deaths….

  15. Are we going to to ignore the fact that one of the news papers said- and I quote "White people affected NOW it's a problem." Like WTF was it not a problem before!

  16. If you survive, hopefully you develop a naturally acquired active immunity. Luckily, no one is crazy enough to check, though.

  17. Thank you so much for telling us about the "media hype" at the end

    people need to be aware of this social destruction of the 21st century

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